About   Help   FAQ
Symbol
Name
ID 		Abl1
c-abl oncogene 1, non-receptor tyrosine kinase
MGI:87859
Phenotype annotations related to hematopoietic system
Darker colors indicate more annotations
Human Phenotypes
Abnormality of blood and blood-forming tissues
Leukocytosis
Abnormal granulocyte morphology
Abnormal basophil morphology
Ph-positive acute lymphoblastic leukemia
Acute myeloid leukemia
Chronic myelogenous leukemia
Myeloproliferative disorder
Thrombocytopenia
Thrombocytosis
Splenomegaly
Disease(s) Associated with ABL1
acute myeloid leukemia
chronic myeloid leukemia

Mouse Phenotypes
abnormal thymus morphology
thymus cortex hypoplasia
thymus atrophy
thymus hypoplasia
decreased thymocyte number
enlarged spleen
abnormal lymphopoiesis
abnormal B cell differentiation
decreased immature B cell number
decreased pro-B cell number
decreased bone marrow cell number
decreased mature B cell number
decreased B cell number
decreased pre-B cell number
abnormal T cell number
decreased T cell number
decreased single-positive T cell number
increased single-positive T cell number
decreased lymphocyte cell number
abnormal spleen morphology
spleen atrophy
spleen hypoplasia
abnormal spleen white pulp morphology
abnormal spleen germinal center morphology
abnormal B cell physiology
abnormal bone marrow cell physiology
abnormal splenocyte physiology
Availability Mouse Genotype
Abl1m1/Abl1m1
Abl1tm1Mlg/Abl1tm1Mlg
Abl1tm1Mlg/Abl1tm1Mlg
Tg(ACTB-Abl1*I)1Spg/0
Abl1tm1Mlg/Abl1tm1Mlg
Tg(ACTB-Abl1*K290R)1Spg/0
Abl1tm1Mlg/Abl1tm1Mlg
Tg(ACTB-Abl1*IV)1Spg/0
Abl1tm2.2Goff/Abl1tm2.2Goff
Tg(Igh-Abl1)40Sco/0
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory